Pharmaceutical technology of sterile liquid solutions and extractive solutions: lecture and practice


Simona Sevastre


pharmaceutical technology, sterile liquid solutions, extractive solutions


As it is known, the homogeneous dispersed systems are molecular dispersions in which the components have mutual affinity. They can be divided into nonsterile and sterile liquid solutions. The first subclass was presented in the previous volume „Pharmaceutical technology of non-sterile liquid solutions – Lecture notes”, 2019, SITECH.

In the first part of these lecture notes, aspects related to the technology of the second subclass - sterile homogenous liquid pharmaceutical forms will be detailed. Due to the fact that extractive solutions are the ones that make the transition to heterogeneous dispersion systems (to be studied in the next semesters of pharmaceutical technology), they will be the subject of the second part of this material.

By providing essential information to create abilities and values necessary in the pharmaceutical field practice, the Pharmaceutical Technology Department is part of the team that contributes to the formation of future pharmacists, real health professionals.

It would be expected that after following these course notes, the Pharmacy students will acquire general notions of bioavailability/ bioequivalence and specific information about compounding (active substances, vehicles, excipients, auxiliaries), stability, packaging (packaging materials) and storage conditions, concerning sterile solutions and extractive solutions. Furthermore, the students will be able to perform common preparation and identification of sterile solutions and extraction products.

The current textbook entitled „Pharmaceutical technology of sterile liquid solutions and extractive solutions – Lecture and practice” was created with the intention to present the available knowledge about sterile liquid dosage forms and extracts in an organized, comprehensive and useful pattern (targeting especially the pharmacy students), but also to consolidate the already acquired data of pharmacy residents, community and hospital registered pharmacists.


February 11, 2021